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姓名:刘帅
联系电话:021-62233286
电子邮箱:sliu@psy.ecnu.edu.cn
通讯地址:华东师范大学心理与认知科学学院认知神经科学研究所 上海市中山北路3663号老图书馆303室 邮编200062
研究方向:动机与奖赏;突触可塑性;享乐性摄食神经机制
个人简介

刘帅 博士

个人简介:

刘帅,博士生导师,现任心理与认知科学学院研究员,脑功能基因组学重点实验室研究员,纽约大学-华东师范大学脑与认知科学联合研究中心(上海纽约大学)客座研究员,上海市浦江人才计划学者,紫江青年学者。博士毕业于复旦大学,曾在加拿大英属哥伦比亚大学、卡尔加里大学Hotchkiss脑研究院担任博士后研究员。主要研究方向为奖赏与动机的神经可塑性机制研究,具有十年以上的电生理学和行为学的研究经验。一系列重要的成果发表于Nature NeurosciencePNASCerebral CortexJournal of Neuroscience, Journal of Neurophysiology等有影响力的SCI期刊。担任Nature Communications, NeuroscienceBrain ResearchFEBS LettersPsychoneuroendocrinology等杂志的特约评审。招生方向:认知科学,神经生物学,神经药理学。

 

研究生招募中,本科专业背景不限,有实验室经历者优先。另招博士后/研究助理一名,熟练使用全细胞膜片钳电生理技术者优先,待遇从优。

 

研究方向:

Dr. Liu’s research goal is to address one of the most fundamental questions in neuroscience: how does the brain work for hedonic feeding. Using a combination of electrophysiology, immunochemistry, behavioral task approaches, the research is conducted in the following three directions:

1. Feeding peptide effects on neuroplasticity in the reward system and hedonic feeding

2. Dissection of neural circuits for motivation and decision-making in hedonic feeding

3. Neural mechanisms underlying metabolic syndrome induced reward circuitry dysfunction

 

 

学术论文

1. Mills F*, Globa AK*, Liu S, Cowan CM, Mobasser M, Phillips AG, Borgland SL & Bamji SX. (2017) Cadherins mediate cocaine-induced synaptic plasticity and behavioral conditioning. Nature Neuroscience. DIO:10.1038/nn.4503

2. Ferrario CR*, Labouèbe G*, Liu S*, Nieh EH*, Routh VH*, Xu S*, OConnor EC. (2016) Homeostasis Meets Motivation in the Battle to Control Food Intake. Journal of Neuroscience. 36 (45) 11469-11481. (* 共同第一作者)

3. Liu S, Globa AK, Mills F, Naef L, Qiao M, Bamji SX, Borgland SL. (2016) Consumption of palatable food primes food approach behaviour by rapidly increasing synaptic density in the VTA. PNAS. 113(9): 2520-2525. DOI: 10.1073/pnas.1515724113

4. Thompson JL, Yang J, Lau B, Liu S, Baimel C, Kerr LE, Liu F, Borgland SL. (2015) Age-Dependent D1-D2 Receptor Coactivation in the Lateral Orbitofrontal Cortex Potentiates NMDA Receptors and Facilitates Cognitive Flexibility. Cerebral Cortex. DOI: 10.1093/cercor/bhv222

5. Liu S, Borgland SL. (2015) Regulation of the mesolimbic dopamine circuit by feeding peptides. Neuroscience. 10: 289C:19-42

6. Ferris MJ, Milenkovic M, Liu S, Mielnik CA, Beerepoot P, John CE, España RA, Sotnikova TD, Gainetdinov RR, Borgland SL, Jones SR, Ramsey AJ. (2014) Sustained NMDA receptor hypofunction remodels the dopamine system and impairs phasic signaling. Eur J Neurosci. 40(1):2255-63.

7. Labouèbe G*, Liu S*, Dias C, Zou H, Wong JC, Karunakaran S, Clee SM, Phillips AG, Boutrel B, Borgland SL. (2013) Insulin induces long-term depression of ventral tegmental area dopamine neurons via endocannabinoids. Nature Neuroscience. 16(3):300-8. (* 共同第一作者)

8. Liu S*, Labouèbe G*, Karunakaran S, Clee SM, Borgland SL. (2013) Effect of insulin on excitatory synaptic transmission onto dopamine neurons of the ventral tegmental area in a mouse model of hyperinsulinemia. Nutrition & Diabetes. 16;3:e97. (* 共同第一作者)

9. Liu S, Zheng P. (2013) Altered PKA modulation in the Nav1.1 epilepsy variant I1656M. J Neurophysiol. 110(9):2090-8.

10. Liu GX, Liu S, Cai GQ, Sheng ZJ, Cai YQ, Jiang J, Sun X, Ma SK, Wang L, Wang ZG, Fei J. (2007) Reduced aggression in mice lacking GABA transporter subtype 1. J Neurosci Res. 15: 85(3):649-55.

 

图书章节:

Liu S, Labouebe G and Borgland S. (2014) Insulin induces long-term depression in VTA DA neurons via an endocannabinoid -mediated mechanism In: Catecholamine Research in the 21st Century. Editor: Lee E. Eiden; p253

 

 

 

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